Comments on “Alzheimer’s biomarker sparks warning about brain-boosting serine supplements”

  1. C Moore says:
    05/04/2022 at 12:44 PM

    With findings like this you have to be cautious about drawing a concrete conclusion like Serine causes Alzheimer’s. It could be people who’ve dealt with it in their family are more inclined to take such supplements, knowing that they may be more susceptible, and therefore have higher blood levels of those micro nutrients.

  2. Dan Orbeck says:
    05/04/2022 at 1:22 PM

    Okay. What are the otc supplements should we avoid?

  3. Dr. David Brady says:
    05/04/2022 at 3:04 PM

    Well, taking serine versus phosphatidylserine (PS) are two very different things. Most knowledgeable nutritional professionals recommend the latter in some of their brain and nootropic protocols, and post-stroke (along with GPC). The PS is generally incorporated in-whole into the neuronal membranes, which is the intention to increase their integrity and fluidity. It does not raise free serine in the brain to my knowledge.

    Also, this press release seems to be trying to make a bunch of hay about one enzyme in the brain (extremely reductionist in itself) that may contribute to making serine be in excess in AD. However, what is the enzyme is being up regulated in AD patients intentionally by the body because it requires more serine to combat it? To me, while interesting and may prompt more deeper research, right mow it seems like more classic myopic PhD researcher stuff turned into flashy headlines.

  4. V Vendetta says:
    05/04/2022 at 3:44 PM

    What supplements have or are Serine booster? Science is interesting but hardly ‘news you can use.’

    1. Kathy says:
      08/31/2022 at 6:56 PM

      Serine. L-serine, D-serine

  5. Hymie Porkenstein says:
    05/04/2022 at 5:18 PM

    I don’t believe anything coming out of Chinese so called scientist

  6. Stephen Fearby says:
    05/04/2022 at 7:10 PM

    Depends on what form of serine that’s being talked about. For example:

    Genetics and Molecular Research (2015)
    Effect of phosphatidylserine on memory in patients and rats with Alzheimer’s disease

    From the Abstract

    “…In AD patients, vocabulary and picture matching scores in the two treatment groups increased after treatment (P < 0.05). Moreover, the scores in the treated group were significantly greater than the control group (P< 0.05)."

  7. K Moore says:
    05/05/2022 at 8:47 AM

    Maybe the body, recognizing that something is wrong, tries to compensate by increasing serine production…

  8. DrBob says:
    07/04/2022 at 11:14 AM

    It seems to me that research must clarify its findings about serine vs phosphatidylserine. And, if taking phosphatidylserine increases the progression and severity of Alzheimers, then the public and nutritional professionals should be informed. Though Alpha GPC has been touted as an excellent supplement, a recent study indicated that if you take it long term, there is a nearly 50% risk of increasing your chance of stroke. That is a significant finding and should be taken seriously especially by those of us who do take supplements long term. In the best interests of their readership, I would encourage to follow up with additional results about and recommendations for the use of phosphatidylserine. Thank you. DrBob


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