Either I overlooked it, or it wasn’t mentioned in the article, but I really am curious to know, how would this cancer protein be collected or extracted from elephants. I’ve been knowing for a very long time now, that the killing of many elephants, from so many evil men, who just kill for their tusks, has about brought these wonderful animals to extinction, and therefore seeing this article, and wondering, would this thing they want from elephants, have men getting it from live elephant, in their natural environment, or would many elephants be rounded up, and set in cages, pens, etc, to collect from them, there, which that option would break my heart! OR the last and again heartbreaking option, be done. Round them up, and kill them all, as this so called protein, is needed?? I hope I can get a knowledgeable person to answer!
Elephants have up to 19 copy number variants “CNV” of TP53 genes. We all have p53 proteins, from TP53 genes. If the TP53 gene is mutated like it is in 50% of cancer, then up regulation of TP53 by down regulation of MDM2 with Beets may not be very effective.
Gerald says:
07/16/2022 at 10:39 AM
Evolution has had nothing to do with making the elephant what it is. Natural Selection did. But this is not evolution. The reasons why elephants are elephants us because their DNA was designed to make them as they are. And that same “armory” of defenses that protect them from cancer, also assures that their DNA could mot over time reproduce descendants that would need to classified differently from the original parent organisms.
Actually… the discovery that elephants have multiple copies of p53 , accounting for their exceedingly low cancer rate of death(“elephants never die if cancer) despite their huge body mass and sheer astronomical number of cells which could theoretically mutate, was made about 10 years ago by geneticists at Primary Children’s Medical Center and at the University of Utah medical school, and was highlighted in a highly read article in Newsweek at the time. A geneticist took his kids to the Salt Lake City zoo and he asked the keeper what kinds of cancers do elephants get? The response… “elephants never get cancer.” Astonished, he made arrangements to return to draw a blood sample to analyze for the p53 gene, already understood to be an important cancer surveillance gene, humans having inky 2 copies. Thus, the discovery was made. The current cited study builds on that foundation by elucidating more of the details about how the protein coded by p53 works to prevent cancer. Resulting from the studies, PCMC developed a working partnership with WBBB Circus to conduct ongoing research and support for their elephant stock which continued until the woketard animal “rights” crowd shut down the circus. One more examples of liberals ruining everything they touch. Sorry to get political, but it’s the truth.
David Boettger MD Pediatrics
Salt Lake City UT
Either I overlooked it, or it wasn’t mentioned in the article, but I really am curious to know, how would this cancer protein be collected or extracted from elephants. I’ve been knowing for a very long time now, that the killing of many elephants, from so many evil men, who just kill for their tusks, has about brought these wonderful animals to extinction, and therefore seeing this article, and wondering, would this thing they want from elephants, have men getting it from live elephant, in their natural environment, or would many elephants be rounded up, and set in cages, pens, etc, to collect from them, there, which that option would break my heart! OR the last and again heartbreaking option, be done. Round them up, and kill them all, as this so called protein, is needed?? I hope I can get a knowledgeable person to answer!
They will just clone the proteins.
Elephants have up to 19 copy number variants “CNV” of TP53 genes. We all have p53 proteins, from TP53 genes. If the TP53 gene is mutated like it is in 50% of cancer, then up regulation of TP53 by down regulation of MDM2 with Beets may not be very effective.
Evolution has had nothing to do with making the elephant what it is. Natural Selection did. But this is not evolution. The reasons why elephants are elephants us because their DNA was designed to make them as they are. And that same “armory” of defenses that protect them from cancer, also assures that their DNA could mot over time reproduce descendants that would need to classified differently from the original parent organisms.
The vaxx will change the human DNA through mRNA.
Sure, take the cure, but then your nose will grow down to the floor.
Actually… the discovery that elephants have multiple copies of p53 , accounting for their exceedingly low cancer rate of death(“elephants never die if cancer) despite their huge body mass and sheer astronomical number of cells which could theoretically mutate, was made about 10 years ago by geneticists at Primary Children’s Medical Center and at the University of Utah medical school, and was highlighted in a highly read article in Newsweek at the time. A geneticist took his kids to the Salt Lake City zoo and he asked the keeper what kinds of cancers do elephants get? The response… “elephants never get cancer.” Astonished, he made arrangements to return to draw a blood sample to analyze for the p53 gene, already understood to be an important cancer surveillance gene, humans having inky 2 copies. Thus, the discovery was made. The current cited study builds on that foundation by elucidating more of the details about how the protein coded by p53 works to prevent cancer. Resulting from the studies, PCMC developed a working partnership with WBBB Circus to conduct ongoing research and support for their elephant stock which continued until the woketard animal “rights” crowd shut down the circus. One more examples of liberals ruining everything they touch. Sorry to get political, but it’s the truth.
David Boettger MD Pediatrics
Salt Lake City UT
I have Multiple Myeloma with deletion of TP53. I wonder if there is new hope for those of us with this complication.