There are dozens of studies, innovations, and research findings released everyday by institutions and clinics across the world. Here’s a look at some of the other notable health reports from May 12.
More State Oversight Needed to Improve End-of-Life Care for Assisted Living Residents
New research looks at end-of-life care in assisted living and found that in states with less rigorous regulations residents were less likely to die with hospice or at home – important markers of quality of care.
As Drug Overdose Deaths Climb, Experts Assess Strategies to Stem the Tide
Stemming the tide of the opioid crisis in rural communities requires taking action to overcome the stigma and health inequity that have increased barriers to recovery from substance use disorder (SUD).
Researchers seek to improve success of chimeric antigen receptor-T cell therapy in non-Hodgkin lymphoma
A study published by researchers from Mayo Clinic Cancer Center at Mayo Clinic in Florida and Case Western, Cleveland Medical Center, investigates the reasons for decreasing remission rates for patients with non-Hodgkin lymphoma treated with chimeric antigen receptor-T cell therapy (CAR-T cell therapy).
New project to improve health of patients with kidney failure
A new project, led by Assistant Professor Jessie Chin, aims to boost HD patients’ commitment to exercise through a long-term motivational interviewing conversational agent (LotMintBot).
Dr. Melody Zeng Receives a Hartwell Foundation Individual Biomedical Research Award
Dr. Melody Zeng, an assistant professor of immunology in pediatrics and a member of the Gale and Ira Drukier Institute for Children’s Research at Weill Cornell Medicine, has received a 2021 Hartwell Individual Biomedical Research Award from The Hartwell Foundation.
Study finds nanomedicine targeting lymph nodes key to triple negative breast cancer treatment
A study led by Duxin Sun, Ph.D., found that targeting the immune microenvironment in lymph nodes and tumors simultaneously led to long-term tumor remission in mice models of metastatic triple negative breast cancer.
Massive single-cell atlas across human tissues highlights cell types where disease genes are active
Now researchers at the Broad Institute of MIT and Harvard have developed a robust experimental pipeline that can profile many more cell types from more tissues than can be studied with other techniques, as well as machine learning methods to put this data together and query the resulting map, or atlas.
Novel Cell Atlas for Multiple Human Tissues Reveals Discoveries Underlying Complex Diseases
Scientists from the Broad Institute of MIT and Harvard have developed a first-of-its-kind cross-tissue cell atlas, and in collaboration with researchers at Mass Eye and Ear, have uncovered new clues for specific cell types and genes involved in complex diseases.
Bacteria with recording function capture gut health status
Researchers from ETH Zurich, University Hospital of Bern and the University of Bern have equipped gut bacteria with data logger functionality as a way of monitoring which genes are active in the bacteria.
Presenting the most comprehensive, cross-tissue cell atlases to date: New findings from the Human Cell Atlas consortium
Researchers with the international Human Cell Atlas (HCA) consortium – whose goal is to map every cell type in the human body, but who until now have mostly focused on studying cells in individual organs and tissues or small tissue subsets – report a major feat: creation of detailed maps of more than a million individual cells across 33 organs, representing the most comprehensive, cross-tissue cell atlases to date.
Protein related to Fragile X syndrome may be a new target for blood pressure medicines
A new study in mice has identified FXR1, a protein in the same family as the one implicated in Fragile X syndrome, as a potential target for creating a new type of blood pressure-lowering medicine, according to preliminary research presented at the American Heart Association’s Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.
Immune cell characteristics mapped across multiple tissues, from early life to adulthood
Two new papers from the Human Cell Atlas shed new light on the types and traits of immune cells that can be found in the human body, from developmental stages to adulthood.
‘Tabula Sapiens’ Multi-Organ Cell Atlas Already Yielding Surprises for Biologists
Now, in a paper published in Science on May 13, 2022, the Tabula Sapiens Consortium, a team of more than 160 experts led by scientists at the Chan Zuckerberg Biohub, has unveiled a massive digital atlas that maps gene expression in nearly 500,000 cells from 24 human tissues and organs, including the lungs, skin, heart, and blood.
Multi-tissue cell atlases lead to leap of understanding of immunity and disease
The Human Cell Atlas goal of mapping every cell type in the human body to transform our knowledge of biology, infection and disease is a milestone step closer with four studies published in Science today (13th May).
Ultrathin fuel cell uses the body’s own sugar to generate electricity
Engineers have developed a glucose power source that could fuel miniature implants and sensors.
Albert Einstein College of Medicine Receives $11 Million Grant to Tackle Post-Traumatic Epilepsy
Now, researchers at Albert Einstein College of Medicine, led by Aristea Galanopoulou, M.D., Ph.D., have received a five-year, $11 million grant from the National Institutes of Health (NIH) to look for novel biomarkers that predict a person’s risk for developing PTE and for treatments to prevent the condition.
Smokers who switch to e-cigarettes may adopt other healthy routines
Adult smokers who shift to using to e-cigarettes may have more chances to improve health and well-being, according to new research from the University of Washington.
Study: Treatment Minimizes Infants’ Opioid-Related Brain Abnormalities
Led by scientists at Cedars-Sinai, this is the first study to report evidence validating the benefits of using medication for opioid use disorder during pregnancy.
Uneven Distribution of Emergency Physician Residency Programs Can Impact Workforce Challenges, New Analysis Finds
A new analysis of the emergency physician resident workforce in Annals of Emergency Medicine finds that while the number of residency programs is increasing, new residency programs are disproportionately located in urban areas in states with existing programs, rather than rural communities with limited access to emergency care.
Sugared proteins called proteoglycans start to give up their secrets
Scientists at Scripps Research have developed a set of methods for the closer study of one of the least-accessible, least-understood players in biology: protein-sugar conjugates called proteoglycans.
Throwing Drug Resistance for a Loop
Now, a team of researchers at Gladstone Institutes led by Leor Weinberger, PhD, and Sonali Chaturvedi, PhD, has developed a novel class of therapeutics, called feedback disruptors, that have the potential to be resistance-proof drugs.
Family Size May Influence Cognitive Functioning in Later Life
A new study at Columbia University Mailman School of Public Health and the Robert Butler Columbia Aging Center, and Université Paris-Dauphine – PSL, found that having three or more versus two children has a negative effect on late-life cognition.
Skin drug treatments may regress dangerous birthmarks and prevent melanoma
Researchers led by investigators at Massachusetts General Hospital (MGH) recently created multiple preclinical models of this condition and used them to show that several drugs can be applied to the skin to cause the lesions to regress, and one topical drug also protected against skin cancer.
New Study Reports Need to Monitor Public Interest in Shopping and Sales of Popular Puff Bar E-cigarette Brand
New research led by scientists at the American Cancer Society (ACS) shows the need for continued surveillance of the changes in shopping interest and sales for Puff Bar, the most preferred brand of electronic cigarettes or e-cigarettes among youth in the United States.
Poll shows impact of menopause and other health issues on older women’s sex lives
Less than half of those experiencing menopause-related symptoms have talked to their health care provider about treatment.
First Mutation-Targeted Bladder Cancer Drug May Be Under-Used
The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
Research Aims to Improve Machines’ Recommendations and Predictions Based on Cause and Effect
JUNDONG LI, University of Virginia assistant professor of electrical and computer engineering, computer science and data science, is conducting research that could help teachers and administrators more accurately determine which learning methods are best for their youngest pupils.
Georgia Tech Researchers Develop Wireless Implantable Vascular Monitoring System
Georgia Institute of Technology researcher Woon-Hong Yeo and his collaborators are trying to improve the odds for patients with development of an implantable soft electronic monitoring system.
Unique binding of Delta variant may explain high transmissibility
Unlike other SARS-CoV-2 variants, the Delta variant can attach to copies of itself, forming larger aggregations, or clumps, of viral particles, suggests a study by scientists at the National Institutes of Health.
Strange dreams might help your brain learn better, according to research by HBP scientists
A new study by researchers from the University of Bern, Switzerland suggests that dreams — especially those that simultaneously appear realistic, but, upon a closer look, bizarre – help our brain learn and extract generic concepts from previous experiences.
Delays in surgery for advanced esophageal cancer result in significantly worse survival than early surgery
Delays in surgery for esophageal cancer did not appear to have much impact on patients’ relative survival for early-stage cancer compared with patients who had surgery early, but they did reduce the relative survival rate by almost half for patients with more advanced disease, according to an analysis of the National Cancer Database (NCDB).
How cells correct errors under time pressure
How does a cell balance risk and speed when dividing? EPFL scientists have developed and experimentally tested the first mathematical theory that describes the cell’s best strategy for dividing safely and efficiently.
Cardiac progenitor cells generate healthy tissue after a heart attack
Following a heart attack, the human body is incapable of repairing lost tissue due to the heart’s inability to generate new muscle. However, treatment with heart progenitor cells could result in the formation of functional heart cells at injured sites.
Breakthrough tech enables seizure localization in minutes
New research from Bin He, in partnership with UPMC and Harvard Medical School, introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Huge study of diverse populations advances understanding of type 2 diabetes
Ongoing worldwide research of diverse populations by an international team of scientists, including a University of Massachusetts Amherst genetic epidemiologist, has shed important new light on how genes contribute to type 2 diabetes.
From cavefish to humans: Evolution of metabolism in cavefish may provide insight into treatments for a host of diseases such as diabetes, heart disease, and stroke
New research from the Stowers Institute for Medical Research examines how cavefish, surface-dwelling river fish that flooded into underground cave systems over 100,000 years ago, developed unique metabolic adaptations to survive in nutrient-scarce environments.