There are dozens of studies, innovations, and research findings released everyday by institutions and clinics across the world. Here’s a look at some of the other notable health reports from May 24.
Polymersomes efficiently deliver siRNA to treat breast cancers in preclinical model
Eugenia Kharlampieva, Ph.D., and Eddy Yang, M.D., Ph.D., of the University of Alabama at Birmingham have demonstrated a 100-nanometer polymersome that safely and efficiently carries PARP1 siRNA to triple-negative breast cancer tumors in mice.
COVID Vaccine Trial Locations Infuenced in Vaccine Efficacy Results
A new study by a University of Arkansas information systems researcher and his colleague at the University of Waikato in New Zealand shows that COVID vaccine trials conducted in geographic locations with low infection rates had higher efficacy results, compared to trials in locations with high infection rates.
May/June 2022 Annals of Family Medicine tip sheet
A new study published in Annals of Family Medicine examined general practitioners’(GP) understanding of appropriate ultrasound use versus how early adopters actually use it in their practices.
New gene identified in arrhythmogenic cardiomyopathy
Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells.
Continuity of Primary Care Reduces Hospitalizations in People with Chronic Kidney Disease
People with chronic kidney disease (CKD) require three- to eight-times higher levels of acute care than the general population for comorbidities such as hypertension, diabetes and cardiovascular disease.
Aging (Aging-US) Sponsors Systems Aging Gordon Research Conference
Aging (Aging-US) is sponsoring the Systems Aging Gordon Research Conference, “Systemic Processes, Omics Approaches and Biomarkers in Aging,” from May 29 to June 3, 2022, at the Grand Summit Hotel at Sunday River in Newry, Maine, USA.
Even in the operating room, team chemistry matters, study finds
But happiness and excitement may be overrated, at least where performance is concerned, suggests new research from the University of Toronto’s Rotman School of Management.
Capturing cortical connectivity close-up
New research from the University of Pittsburgh shows that generating detailed maps is indeed possible with a new imaging method that offers high contrast and high spatial resolution.
High Social Vulnerability Predicts Worse Long-Term Outcomes After Traumatic Injury
A team of investigators led by Juan P. Herrera-Escobar, MD, MPH, of the Brigham’s Center for Surgery and Public Health, found that living in an area with higher social vulnerability is strongly associated with worse mental and physical health outcomes after a traumatic injury.
Stepped wedge cluster randomized trials present advantages, challenges in comparison to other research methodologies for primary care practice improvements
The Stepped Wedge Cluster Randomized Trial is a research methodology that has been growing in popularity, particularly for pragmatic implementation and dissemination trials.
While the fetal clock develops, mom’s behavior tells the time
During fetal development, before the biological clock starts ticking on its own, genes within the fetus’s developing clock respond to rhythmic behavior in the mother, according to a new study publishing May 24th in the open-access journal PLOS Biology by Alena Sumová and colleagues of the Czech Academy of Sciences in Prague.
Data contradict fears of COVID-19 vaccine effects on pregnancy and fertility
New experiments conducted in mice add to mounting evidence in opposition to a popular claim that COVID-19 vaccination during early pregnancy may cause birth defects or fetal growth problems.
Hospital readmission rates for patients with symptoms of depression decrease with post-discharge support
New research published in the Annals of Family Medicine examined whether an enhanced 12-week post-discharge telehealth program would lead to reduced hospital readmission among patients who were hospitalized for a medical illness and tested positive for moderate to severe depressive symptoms while being cared for inpatient.
Canadian eConsult services provided much-needed Covid information, specialty consults for primary care doctors
Researchers in Ontario, Canada, conducted a study to assess the impact of utilizing an electronic consultation (eConsult) service to provide timely access to COVID-19 specialist advice for primary care practitioners.
Electronic consultations improve primary care physicians’ access to subspecialty advice and reduce costly, inconvenient patient referrals
A new study in the Annals of Family Medicine examines usage data from a provincial electronic consultation (eConsult) service in Ontario, Canada, which facilitates rapid and secure communications between primary care physicians and subspecialists.
Australia touts success of dedicated general practice respiratory clinics during Covid pandemic
In a special report, Australian researchers describe the national rollout of General Practice Respiratory Clinics (GRPCs) at the onset of the COVID-19 pandemic.
Lung ultrasounds in the primary care setting could save time in the diagnosis of community-acquired pneumonia
Researchers in Spain have conducted a study to compare the diagnostic accuracy of lung ultrasounds (LUS) performed in the primary care setting to chest X-rays (CXR) performed by a radiologist when diagnosing community-acquired pneumonia (CAP).
More guidance needed for primary care physicians who perform ultrasound diagnostics
A new study published in Annals of Family Medicine examined general practitioners'(GP) understanding of appropriate ultrasound use versus how early adopters actually use it in their practices.
Silk layer improves function of surgical masks
University of Cincinnati researchers found that a double layer of silk in combination with a surgical mask can enhance its ability to prevent the spread of viruses like COVID-19.
Antibiotic Use Associated with Inflammatory Bowel Disease in Older Adults
The more antibiotics prescribed to patients 60 and older, the more likely they were to develop inflammatory bowel disease, suggesting antibiotic use could explain some of the growth in Crohn’s disease and ulcerative colitis in older people, according to a review of 2.3 million patient records in a study selected for presentation at Digestive Disease Week® (DDW) 2022.
Gallstone Disease Shown to be Strong Predictor of Pancreatic Cancer
Patients with pancreatic ductal adenocarcinoma (PDAC) were six times more likely to have had gallstone disease within the year prior to diagnosis than non-cancer patients, suggesting gallstones could be a warning sign for this aggressive and deadly cancer, according to research to be presented at Digestive Disease Week® (DDW) 2022.
Alarming Rise Found in Esophageal Cancer and Barrett’s Esophagus in Middle-Aged Adults
Adults aged 45 to 64 experienced a nearly doubled rate of esophageal cancer and a 50 percent increase in the precancerous condition Barrett’s esophagus between 2012 and 2019, according to a database analysis of roughly five million patients to be presented at Digestive Disease Week® 2022.
Listening can be exhausting for older cochlear implant users #ASA182
Degraded acoustic signals can make hearing difficult for anyone, but differences in cognitive abilities, age-related changes, and the use of cochlear implants may exacerbate the problem.
Liver Transplants from Drug Overdose Deaths Rose Sharply During COVID-19 Pandemic
Liver transplants from drug overdose donors rose significantly in the pandemic’s first year, helping keep the number of liver transplants in the U.S. stable despite COVID-19 disruptions, according to a study to be presented at Digestive Disease Week® (DDW) 2022.
Medicare Program Spent $1.8 Billion in 2019 on Drugs Without Confirmed Clinical Benefits
The U.S. federal government spent an estimated $1.8 billion in Medicare funds in 2019 on drugs whose clinical benefits have yet to be confirmed by the Food and Drug Administration, a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health suggests.
The BrightFocus Foundation grants an Alzheimer’s Disease Research Standard Award to a CNIC project
The US nonprofit organization BrightFocus Foundation has granted an Alzheimer’s Disease Research Standard Award to the project ‘Understanding the impact of midlife cardiovascular risk factors & subclinical atherosclerosis on brain health: a role in Alzheimer´s disease’.
Type 2 diabetes accelerates brain aging and cognitive decline
Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.
Stem Cell Cloning Experts Unraveling Cystic Fibrosis
Two nationally recognized experts in cloning and stem cell science from the University of Houston are taking the first step toward limiting the consequences of chronic inflammation in cystic fibrosis (CF) by identifying the source of this persistent and enigmatic inflammation in CF lungs.
Researchers at OHIO receive prestigious NIH grant to create undergrad summer program focused on diabetes research
A summer program for undergraduate students who plan to pursue a graduate or medical degree related to diabetes research will be launched at Ohio University in 2023 thanks to support from a prestigious National Institutes of Health Research Education Program (R25) grant.
How eating eggs can boost heart health
Researchers have shown how moderate egg consumption can increase the amount of heart-healthy metabolites in the blood, publishing their results today in eLife.
Sidekick Microbubbles Carry Anti-Cancer Drugs, Damage Tumor Vessels #ASA182
Microbubbles can assist with localized drug delivery in a patient’s body by popping at a target site to create enhanced permeability of tumor blood vessels.
Most Parents Welcome Use of AI in Pediatric Emergency Department, But Reservations Remain
Parents are generally receptive to the use of artificial intelligence (AI) tools in the management of children with respiratory illnesses in the Emergency Department (ED), according to a survey from Ann & Robert H. Lurie Children’s Hospital of Chicago.
Blood Biomarker Predicts Complicated Crohn’s Disease Years Before Diagnosis: Study
An international team led by a University of Toronto researcher has found that an antibody detectable in blood predicts severe Crohn’s disease and is detectable up to seven years prior to disease diagnosis.
Insilico Medicine announces novel 3CL protease inhibitor preclinical candidate for COVID-19 treatment
Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.
A Titanic Medical Discovery
Scientists from the Tokyo Medical and Dental University (TMDU) used photoelectrochemical measurement and X-ray photoelectron spectroscopy to clarify the source of titanium’s biocompatibility when implanted into the body, as with hip replacements and dental implants.
Teens with Access to Firearms Found to Be at Higher Risk for Suicide
Adolescents who had access to firearms had about 1.5 times higher odds for prior suicide attempt and current suicidal ideation, according to a study published in the journal Academic Pediatrics.
World-first discovery of cornea T cells protecting eyes from viral infections
The cornea – the transparent protective outer layer of the eye critical to helping us see – produces a delicate and limited immune response to fight infections without damaging our vision, according to a ground-breaking new study from the Peter Doherty Institute for Infection and Immunity (Doherty Institute).
Researchers Shed Light on Genetic Mechanisms of Wilms Tumor
New research from Ann & Robert H. Lurie Children’s Hospital of Chicago and collaborators from other institutions provides insights into some of the genetic characteristics resulting in the development of relapse in patients with Wilms tumor (nephroblastoma), the most common type of pediatric cancer of the kidney.
Harmless cells transform into ruthless trained killers
Processes in the human body could turn groups of harmless immune cells into ruthless killers, capable of attacking other cells infected with viruses or parasites, and potentially tumour cells, a new study reveals.
Low stroke risk in patients with very narrowed neck arteries
The risk of having a future stroke caused by a severe blockage in an artery in the neck that is not currently causing any symptoms is so low that most patients with this condition — asymptomatic carotid stenosis — could potentially be treated with the newest medications and may not require surgery, new Kaiser Permanente research suggests.
Common diabetes drug not effective against early-stage breast cancer, landmark trial reveals
A widely used and inexpensive Type 2 diabetes drug, once hoped to hold enormous promise in treating breast cancer, does not prevent or stop the spread of the most common forms of the disease, according to new findings.