Supplement capsules

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Glucosamine is a natural substance in cartilage, and it plays a vital role in cushioning joints. As we age, our bodies produce less glucosamine, which can lead to joint pain, stiffness and reduced mobility. Fortunately, glucosamine supplements are a popular way to provide relief from arthritis, joint pain and inflammation. However, with lots of glucosamine supplements available, it can be difficult to figure out which one is right for you. To help, we’ve compiled a list of the best glucosamine supplements that experts recommend.

Glucosamine, the joint-pain lifesaver, might just be the key to a longer life. A study by West Virginia University found that taking glucosamine/chondroitin supplements daily for a year can reduce your risk of death by a whopping 39 percent even after considering age, sex, smoking habits and exercise levels. Additionally, they found a link between glucosamine and a 65 percent lower risk of cardiovascular-related fatalities. So, not only will your joints thank you, but your heart will, too. 

However, certain physical activities can accelerate joint degeneration, putting you at greater risk of developing osteoarthritis. Racket sports, in particular, have been found to be among the worst physical activities for your knees, according to a study by the Radiological Society of North America. This is especially true if you’re carrying a few extra pounds. With nearly 14 million Americans affected by osteoarthritis, it’s not something to take lightly.

Therefore, with so much research behind glucosamine, you may be wanting to try the supplement for yourself. After all, adding it to your daily routine could be life changing, especially if you’re suffering from joint pain, stiffness or reduced mobility. Glucosamine can offer relief from arthritis and inflammation, and potentially even reduce the risk of cardiovascular-related fatalities and overall mortality. To help you choose the right product, read on for the list of the best glucosamine supplements experts say money can buy. Leave us a comment if you’ve found success in a glucosamine supplement and which one you use!

The List: Best Glucosamine Supplements, According to Experts


1. Physio Flex Pro Total Joint Support

Experts say this is a must-try for those who suffer from chronic joint pain. SFGATE claims it’s an award-winning formula: “Named the Best Joint Supplement of 2023 by many online health magazines, Physio Flex Pro was developed by a team that includes a certified physiotherapist and trainer. Physio Flex Pro has received numerous accolades and endorsements … earning it the top position on our list. The advanced formula contains a precise dose of natural compounds said to ‘turn back the clock’ and give you the ability to do the things you used to do before joint pain took over your life.” 

Physio Flex Pro Total Joint Support
Physio Flex Pro Total Joint Support

“One of the best supplements you can take for painful joints is Physio Flex Pro. This top-rated supplement helps those suffering from arthritis pain and chronic joint pain to live pain-free and restore joint function. The research-based formula uses natural ingredients to alleviate joint pain by nourishing and lubricating the joints. Physio Flex Pro works by using joint lubrication to alleviate joint stiffness and restore mobility. It also helps protect joints by repairing connective tissue using all-natural compounds,” The Dallas Morning News reports.

BarBend says it’s worth the cost: “Physio Flex Pro is a super stacked joint supplement and aims to promote mobility, flexibility, lubrication, and strength in joints. If you opt for a one month supply of Physio Flex Pro it will cost you around $2.00 per serving, which is more expensive than some other options on the market, but [its] anti-inflammatory and joint health-boosting ingredients make it more robust and multifaceted than most others. They also have bulk buy options that go up to a five month supply.” 

2. Performance Lab Flex

Men’s Journal thinks this is the ideal supplement for athletes: “Performance Lab Flex allows you to reach peak physical performance. Active lifestyles often lead to joint injury, no matter how healthy we are or how much we prepare. Performance Lab Flex is specifically designed for athletes and highly active people who suffer joint pain from injury or overuse. The joints are also lubricated and nourished, leading to fewer chances of damage in the future.” 

Performance Lab Flex
Performance Lab Flex

Orlando Magazine writes, “This all-natural supplement is suitable for people with arthritis and joint problems. It combines glucosamine and chondroitin with herbs and nutrients to support the joints, tendons, and ligaments. In addition, it prevents free radicals from damaging joints and other connective tissue. Moreover, it is vegan friendly and suitable for all ages and dietary preferences.”

We really like that Performance Lab has taken great measures to ensure its products are clean and free of unwanted additives. Supplements are first tested in-house by their quality control team and then sent to a third-party lab to continue testing for composition, purity, and potency. The company makes an effort to be eco-conscious by using only recyclable containers and packaging, and choosing eco-friendly ingredient options whenever possible,” Active claims.

3. Relief Factor Quick Start 

Experts say this is an effective joint pain supplement that won’t break the bank. According to HealthCanal, “If you’re looking for an affordable joint health supplement with proven ingredients, Relief Factor is worth trying. Relief Factor is designed to help alleviate joint pain associated with exercise, aging, and everyday living. The formula is 100% drug-free and made with icariin, turmeric, resveratrol, and omega-3 to support your body’s natural healing process and help reduce pain and inflammation.”

Relief Factor Quick Start Joint Supplement
Relief Factor Quick Start Joint Supplement

“Relief Factor is the most popular joint pain pill on the market in the US right now. The blend of Turmeric, Resveratrol and Omega 3 fatty acids is a pretty good all around option,” says.

4. Arazo Nutrition Glucosamine Chondroitin Joint Support Supplement

FOX31 gives you the need-to-know details, writing, “This option contains a blend of supplements with evidence of benefits in relieving symptoms due to arthritis including joint pain, stiffness and inflammation. What you’ll love: It contains high-strength glucosamine, which allows for a convenient once-daily dosage. The supplement has been tested by a third party and is made in a GMP-certified facility.” 

Arazo Joint Suppot Supplement
Arazo Joint Suppot Supplement

“Arazo Nutrition Joint Support is an advanced formula of high-quality ingredients that help repair cartilage, boost joint mobility, and increase joint flexibility. This supplement is made in a GMP-certified facility in the United States and is third-party safety tested for purity,” Jacked Gorilla claims.

5. Garden of Life FYI Ultra

This is a comprehensive joint and cartilage support supplement that may help reduce joint pain and support overall joint health. WTKR reports, “Garden of Life FYI Ultra Ultimate Joint and Cartilage Formula has a unique blend of pomegranate, olive leaf, and astaxanthin extracts that are high in antioxidants and can help the body fight off free radical oxidative stress. [It’s a] vegetarian-friendly product … [and] will help to eliminate joint pain, inflammation, and stiffness to a noticeable degree.” 

Garden of Life FYI Ultra
Garden of Life FYI Ultra

Shellfish-free glucosamine, selenium, boswellia, ginger, and turmeric come together to keep joints strong in this supplement. From there, Garden of Life adds a unique blend of astaxanthin, olive leaf, and pomegranate — antioxidant-rich extracts that can help the body combat free radical oxidative stress. We appreciate that Garden of Life is a B Corp Certified company, and the carbon footprint of this product is completely offset by reduction projects,” MindBodyGreen explains.

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Note: This article was not paid for nor sponsored. StudyFinds is not connected to nor partnered with any of the brands mentioned and receives no compensation for its recommendations. This post may contain affiliate links. 

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