Stress ball

Improving handgrip strength can help slow down neuronal aging. (Photo by New Africa on Shutterstock)

Just four weeks of handgrip training helped older adults send nerve signals faster, hinting at a simple way to keep reflexes sharp.

In A Nutshell

  • Four weeks of handgrip training sped up nerve signal speed in both young and older adults.
  • Older adults improved as much as younger ones, showing nerves remain adaptable with age.
  • Nerve changes appeared before strength gains, especially in older adults.
  • Simple at-home exercises may help reduce fall risk and support independence.

SYRACUSE, N.Y. — Just four weeks of handgrip exercises helped older adults send nerve signals faster, according to new research. The study shows that simple, at-home training may help offset one of aging’s most stubborn effects: slowing of the nerves that control movement.

Researchers tested whether resistance training could improve nerve conduction velocity, the speed at which electrical signals travel from the spinal cord to muscles. Both younger and older participants improved by about 5.6% after a month of training. Faster nerve signaling may mean sharper reflexes and better protection against falls.

“We did not expect the magnitude of adaptations demonstrated in this study from such a short intervention,” the researchers explained in their paper, published in Medicine & Science in Sports & Exercise. They emphasized that the four-week period was chosen mainly for convenience, not because it represents the optimal training window.

Aging Doesn’t Block Nerve Adaptability

The study included 48 adults between the ages of 18 and 84. They were divided into four groups: young training, young control, older training, and older control. Participants in the training groups used specialized handgrip kits containing adjustable grippers, stress balls, grip rings, and finger stretchers. They trained three times per week for 30–45 minutes.

Older adults adapted just as much as younger ones. This finding surprised the researchers, who expected smaller gains in older participants based on past evidence from muscle training studies. Instead, both age groups showed nearly identical improvements in nerve conduction speed.

This challenges the idea that the nervous system becomes too rigid to respond to exercise later in life. While muscle size and strength gains do tend to be smaller with age, nerve speed appears to remain more adaptable.

To measure each subject’s nerve conduction velocity for their study, researchers Jason DeFreitas (pictured far right) and JoCarol Shields used nerve conduction tests that stimulated the nerves in the muscles of the forearm and measured how fast it took to activate the muscle.
To measure each subject’s nerve conduction velocity for their study, researchers Jason DeFreitas (pictured far right) and JoCarol Shields used nerve conduction tests that stimulated the nerves in the muscles of the forearm and measured how fast it took to activate the muscle. (Credit: Syracuse University)

Why Nerve Conduction Matters

As people get older, their peripheral nervous system gradually slows. Motor neurons lose axons, and surviving fibers conduct impulses less efficiently. This slowdown can mean delayed reactions, poorer coordination, and higher risk of falls.

Falls are a leading cause of serious injury in older adults, which makes even modest improvements in reaction time meaningful.

Healthy young adults usually show conduction speeds around 60–70 meters per second, but this naturally declines with age. By finding a way to speed signals back up, the study points toward an accessible way to protect mobility.

The Training Approach

Participants followed a straightforward program designed to be practical at home. Handgrip kits included grippers with adjustable resistance, rings ranging from 10 to 50 pounds, and finger stretcher bands ranging from 8 to 21 pounds. Each session combined grip strengthening and finger extension exercises.

Nerve conduction velocity was measured using electrodes placed on participants’ forearms. Small electrical stimulations tested how quickly the median nerve carried signals. Pre- and post-training results showed that nerve signal speed increased in both younger and older groups, while control groups showed no meaningful change.

Both younger and older adults improved by about the same amount, showing that even a short, simple program can make a noticeable difference in just a month.

Nerve Gains Come Before Strength Gains

Interestingly, while the young training group also gained grip strength, the older group did not see statistically significant strength increases. Yet both age groups improved equally in nerve conduction.

This suggests that nerve system adaptations occur before noticeable muscle gains, at least in short interventions. Longer training may be needed for older adults to show strength improvements.

Degradation of motor neurons, conceptual 3D illustration.
Degradation of motor neurons, conceptual 3D illustration. (Image by Kateryna Kon on Shutterstock)

How Might Nerves Get Faster?

The study cannot say for certain why nerves sped up, but several possible explanations exist:

  • Axonal diameter: Wider nerve fibers conduct signals faster. Just as larger pipes allow faster water flow, thicker nerves may carry impulses more quickly.
  • Myelin changes: Nerves are insulated by myelin sheaths. Training might improve myelin quality or repair mild age-related thinning.
  • Neuromuscular junction efficiency: Better communication at the point where nerves connect to muscles could improve conduction speed.
  • Increased excitability: Training may make nerves more responsive to stimulation.

Researchers stress that these are hypotheses, not proven mechanisms. More precise imaging studies will be needed to test them.

Unlike complex rehabilitation programs, grip training requires little equipment, minimal space, and can be done at home. If follow-up studies confirm these results, healthcare providers may be able to recommend handgrip training as a low-cost strategy to help older adults maintain nerve health.

The researchers note several limitations: the short study duration, reliance on self-reported training logs, and a mostly female sample. Some older participants were already active in racket sports, which may have influenced results. Still, nearly every participant in the training groups improved, an outcome that was not expected.

The Takeaway

A month of handgrip exercises measurably sped up nerve signaling in both younger and older adults. The improvements suggest that the nervous system retains adaptability throughout life, even when muscles may respond more slowly to training.

Here’s a supplemental article we’ve provided to help you build your handgrip strength at home through simple training exercises.

Resistance training, even in simple forms, may help offset age-related nerve slowing. This could reduce fall risk and support independence for older adults. More research is needed to see whether longer programs produce lasting changes and to uncover the exact biological mechanisms.

For now, this study highlights a hopeful message: it is never too late for the nervous system to respond to training.

Disclaimer: This article is for general informational purposes only and is not a substitute for medical advice. Always consult a healthcare professional before starting a new exercise program.

This article contains affiliate marketing links to Amazon for handgrip strength kits, through which StudyFinds earns a commission if you make a purchase. We are grateful for your support.

Paper Summary

Methodology

This randomized controlled study involved 48 participants aged 18-84, divided into four groups: young training, young control, older training, and older control. Participants completed four weeks of handgrip resistance training using specialized kits containing adjustable grippers, stress balls, grip rings, and finger stretchers. Training occurred three times per week for 30-45 minutes per session with progressive resistance from 10-50 pounds for grip rings and 8-21 pounds for finger stretchers. Researchers measured median motor nerve conduction velocity using electrodiagnostic equipment with electrodes placed on the forearm before and after the intervention period. Maximal handgrip strength was also assessed using a hand dynamometer.

Results

Both young and older training groups showed significant 5.6% increases in nerve conduction velocity after four weeks (young: p < 0.001, Cohen’s d = 0.749; older: p < 0.001, Cohen’s d = 0.679), while control groups showed no significant changes. Only the young training group demonstrated significant improvements in grip strength for both arms (left: p = 0.001; right: p = 0.004). Surprisingly, age did not affect the magnitude of nerve conduction improvements, contradicting the researchers’ hypothesis that older adults would show smaller adaptations.

Limitations

Several limitations may have influenced the results. Participants were classified as “untrained” but were allowed up to two exercise sessions per week, and several older adults reported being active in racket sports. Four weeks may have been too short to detect strength changes in older adults. Compliance relied on self-reported training logs rather than direct supervision. The study population was predominantly female, potentially introducing gender bias. Additionally, the researchers could not definitively determine the underlying mechanisms responsible for the nerve conduction improvements.

Funding and Disclosures

This project was funded in part by a Doctoral Research Grant awarded through the Central States chapter of the American College of Sports Medicine (CSACSM). The authors declared no conflicts of interest, financial or otherwise, and stated that results are presented clearly and honestly without fabrication, falsification, or inappropriate data manipulation.

Publication Information

Shields, J.E., Smith, C.M., Reese, S.M., Dos Santos, M.L., Parodi, M., and DeFreitas, J.M. “An Exercise Intervention May Counteract the Degradation of Nerve Conduction from Age-Related Disuse.” Medicine & Science in Sports & Exercise, Vol. 57, No. 10, pp. 2101-2107, October 2025.

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