FAIRFAX, Va. — Insecticides may impair a man’s fertility, a new study warns. The research, examining 25 studies spanning almost five decades, found a strong link between exposure to these toxic chemicals and reduced sperm counts in adult men. This systematic review presents consistent and robust evidence of an association between insecticide exposure and lower sperm concentration.
The researchers, led by Dr. Melissa Perry, Dean of the George Mason University College of Public Health in the United States, advocate for policies to limit men’s exposure to insecticides, particularly those planning to father children.
“Understanding how insecticides affect sperm concentration in humans is critical given their ubiquity in the environment and documented reproductive hazards. Insecticides are a concern for public health and all men, who are exposed primarily through the consumption of contaminated food and water,” says Lauren Ellis, MPH, a doctoral student at Northeastern University, in a media release.
The team reviewed nearly five decades of human studies on the health impacts of two common insecticide classes: organophosphates and N-methyl carbamates. They consistently found associations with lower sperm counts, a concern that Dr. Perry emphasized, especially considering other studies pointing to a general decline in semen quality.
Dr. Perry stressed the inherent nature of insecticides as substances designed to kill, underscoring the substantial evidence that supports reducing exposure, especially among men planning to start families. The team expressed surprise at the robustness of their findings.
Finally, the researchers call for policymakers to take this evidence into account, making decisions to decrease individual exposure to insecticides and recognize it as a significant public health issue.
“This review is the most comprehensive review to date, sizing up more than 25 years of research on male fertility and reproductive health. The evidence available has reached a point that we must take regulatory action to reduce insecticide exposure,” says Dr. Perry, the senior author of the paper.
The findings are published in the journal Environmental Health Perspectives.
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South West News Service writer Stephen Beech contributed to this report.
Fenbendazole is a frequently used medication that belongs to the benzimidazole group of drugs. This drug works by disrupting the energy production of parasites, making them unable to survive. Such parasitic infections are a tremendous health concern, affecting people and animals all over the world. Common parasites that cause these infections are roundworms, hookworms, whipworms, and tapeworms.
Parasitic infections may not cause visible symptoms right away, but prolonged exposure can lead to various difficult health issues, such as nutrient deficiency, cravings for certain foods, discomfort and swelling in the stomach, anemia, chronic exhaustion, higher body temperatures, sweat during the night, painful muscles and joints, skin issues such as rosacea, and itching in the anal and vaginal regions.
Fenbendazole has earned a reputation as a potent therapeutic remedy for intestinal parasites. Its ability to tackle many different kinds of parasites causes it to be regularly suggested as a therapy for diverse worm infections, such as strongyloidiasis, trichuriasis, and enterobiasis.
Fenbendazole has a distinct way of functioning as it is directed at a particular protein named beta-tubulin which is present in the narrow tube-like structures found in parasites. Microtubules are vital for a number of cellular processes such as cell duplication and procreation.
When a parasite ingests fenbendazole, the medication binds to the beta-tubulin within the microtubules, hindering the construction of these microtubules. Therefore, the parasite’s capacity to multiply its cells is hindered, unsurprisingly disrupting its reproductive aptitude.
Fenbendazole stops the parasite’s ability to metabolize glucose, which it needs for fuel. As a result, the organism starts to lose energy, and when it is deprived of that, it perishes.
Fenbendazole is recognized for its accuracy, as it only acts upon the beta-tubulin of the parasites while not influencing the same element in the creature that is being treated. This is why fenbendazole is considered as an effective and safe way to address parasite invasions in many cases.