ADELAIDE, Australia — Your risk for cancer may be linked to something deep inside your body. Australian researchers have established a significant connection between a person’s cancer risk and the functions of circular RNAs (circular genetic fragments) found within our cells. The findings reveal that specific circular RNAs can bind to DNA in our cells, leading to DNA mutations that can cause cancer.
“While environmental and genetic factors have long been believed the major contributors to cancer, this revolutionary finding – which we call ‘ER3D’ (from ‘endogenous RNA directed DNA damage’) – ushers in an entirely new area of medical and molecular biology research,” explains Flinders University Professor Simon Conn, who leads the Circular RNAs in Cancer Laboratory at the Flinders Health and Medical Research Institute, along with his wife, Vanessa.
To uncover the link between circular RNAs and cancer, researchers compared the neonatal blood tests of infants who later developed acute leukemia with those who did not have any blood disorders. They discovered that a specific circular RNA was present at significantly higher levels in infants who developed leukemia, even before the onset of symptoms. These findings suggest that the abundance of circular RNA molecules within certain individuals’ cells is a major determining factor in why some individuals develop cancer-causing genes or oncogenes, while others do not.
Circular RNAs have the ability to bind to DNA at various locations in different cells. By binding to specific sites on DNA, they initiate changes that result in DNA breakage, which the cell must repair to survive. However, this repair process is not always flawless and can lead to small mutations, akin to misspelled words in a book, or more severe cases, significant and devastating mutations.
Moreover, circular RNAs can also alter the physical location of the broken DNA within the cell nucleus, causing two distinct regions of the DNA to fuse during the repair process, like merging the pages of different books. Prof. Conn notes that multiple circular RNAs seem to work in partnership, causing breaks at multiple DNA sites. This process, called chromosomal translocation, poses a significant challenge to cells as it results in gene fusions that can transform normal cells into cancerous cells. The researchers demonstrated this phenomenon in two different cell types, observing its role in the rapid onset of aggressive leukemia.
The gene fusions resulting from the action of circular RNAs occur at well-known mutation “hotspots” in leukemia. This has critical implications for Australia, which has the highest incidence of leukemia worldwide, with approximately 35,000 Australians currently living with the disease. These gene fusions have long been utilized by doctors worldwide to guide treatment decisions due to their negative impact on patient prognosis.
Dr. Conn emphasizes that ER3D is not exclusive to leukemia; the process extends to other types of cancer and human diseases. The research team at Flinders University is dedicated to further investigating the role of circular RNAs in cancer and other diseases, paving the way for improved understanding and potential therapeutic breakthroughs.
“This is the first example of a genetic molecule present in many individuals that has the ability to mutate our own DNA and drive cancer from within,” explains Vanessa Conn. “This breakthrough opens doors for using these molecules as therapeutic targets and disease markers at an early stage when the chances of successful treatment are higher.”
The study is published in the journal Cancer Cell.
I’ll give you the biggest trigger of cancer…. It’s called money… healthcare… and big pharma
The American Diet is the cause of cancer. Money, healthcare and big pharma thrive on it.
RNA culprit played major role in Covid19 vaccines. There’s no connection.
Money? In 2021 my wife was diagnosed with AML Leukemia with Flt mutation. She had a bone marrow transplant, everything went well and she is at this moment cancer free. But she has to take a med to keep the mutation quiet. The med is Xospata and costs (hold on now) $31,000 a month. It was $23,000 a month when she started the med in Oct 2021.
Here is the USA we are the nation that people go bankrupt over medicines. Yep pharma is big money. Insurance has helped but we have a 20% co-pay and without insurance we could never afford the med. I have a letter on my desk, as of August 2, 2023 the pre-authorization for them paying the med costs is ending. So that will be the end of her getting the meds.
Should be Dr. Vanessa Conn.
Is this the same as mRNA? The main ingredient in the C19 vaccines. They were all the rage a couple years ago. If you didn’t take it you were a outcast, a bigot, a terrible human.
Will these vaccines have an impact on people becoming more susceptible to Cancer?
Most people won’t spend a few of their ill gotten shekels on the only proven cancer prevention;Brown Seaweed Extract.
I will. Post the evidence so we can see what you mean.
You lost me at “shekels”.
Hey Author, any info on when testing for these “circles” begins on the masses?
Well, I have 2 revolutionary explanations:
1. God is a gambler
2. Life sucks
Brown seaweed extract.Ill get some. What about Essiac?
Correlate “vaccination” with cancer. SV40 in most polio vaccines is the best place to start.
If my sister got stomach cancer but it all gone will other people in our family get cancer too
Wondering how this circular DNA would apply to identical twins. My husband has Multiple Myeloma and his identical twin does not. Would this study indicate that will develop in his future?
Genes + Environment interaction over time.
Genes that are less susceptible to environmental triggers.
Balanced micro environment which is nutrients consumed and minimum exposure to unhealthy macro environment such as air and water quality.
William branham,gods last prophet messenger said its of demons. He had a healing ministry millions were healed by faith in jesus!!!!!!
William m branham was rev 10 messenger.
Compare this study, with this hypothesis on pubmed:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876036/?fbclid=IwAR3KumJNi9fzKhfCBeVF8-zK8T9GpWMC1koigiWz7X8elOsAyJX6LtPYubg
In certain individuals, covid vaccines could exacerbate this issue.
Look at all the nut-case comments once this article was linked to drudgereport!
Never believe a trumper about health-benefits!
Drudge is anti-Trump and has been for a while. “Trumpers” don’t go there. Try to keep up.
Why are they not accepting the FACTS are so simple as is to why we are dying of cancer?
AIR POLLUTION
WATER CONTAMINATION
FOOD BORNE PARASITES
FDA APPROVED MEDICATIONS
NON FDA MEDICATIONS
PRESERVATIVES
ADDITIVES
TOXIC IS ALL THAT WE CONSUMR AND ALL WE’VE BEEN SUBJECTED TO IN THIS WORLD OF GREED, GLUTTONY, ENVY, PRIDE,LUST, AND HOW MUCH I HAVE BECOME A NARCISSE MYSELF.
No one in the monarchy have cancer… all death for all age relate … the poor worker have all deadly problems…genocide every where… the sect in the darkness of monarchy create all the conditions to exterminate the human consciens..who are the only one to by able to salve and defending animals and the mother earth…