Woman applying deodorant to her underarms

Woman applying deodorant (Photo by Prostock-studio on Shutterstock)

In a world where confidence is key, few things are as embarrassing as when your deodorant cracks under pressure. Fortunately, not all deodorants are created equally. Formulated for maximum effectiveness, the best clinical strength deodorants provide excellent protection against unwanted odors and wetness. 

In fact, it’s more than just protection with clinical-strength deodorants. With comfort making a strong debut, clinical strength deodorants keep you feeling fresh and dry from dawn to dusk. This is important for our self-esteem, as a newer study found that over 65 percent of adults have ended relationships due to ick factors. Of those factors, 24 percent found that smelling bad is the top ick factor. 

Unfortunately, the side effects of using bad deodorant don’t stop there. According to a recent study, researchers from the University of Queensland say an ingredient found in some popular toothpaste, deodorant, and shaving gel products may be contributing to antibiotic resistance. With more than 700,000 antibiotic-resistance deaths reported annually, it serves as a chilling reminder that we don’t only have to look at what we put into our bodies, but on our bodies as well. 

So, are you ready for complete odor control? To learn about the best clinical-strength deodorants, we’ve compiled a list for you. Providing all-day protection against sweat and odors, these clinical-strength deodorants will have you questioning how you ever lived without them. Don’t happen to see your favorite deodorant on the list? Drop us a comment and let us know!  

A woman holding deodorant (Photo by CottonBro Studio on Pexels.com)

The List: Best Clinical-Strength Deodorants, Most Recommended By Experts


1. Secret Clinical Strength    

“Created in partnerships with dermatologists, Secret Clinical Strength helps reduce sweating three times as much as other brands,” writes People. With outstanding odor-blocking benefits, this deodorant is formulated with “provitamin B5 to help protect the skin and retain moisture while preventing excessive sweating.” As a stick gel-based formula, the “smoothy and silky texture” of this deodorant helps you remain comfortable and sweat-free all day long. 

Secret Clinical Strength   
Secret Clinical Strength

“We loved the crisp lavender scent, which was feminine and not overpowering,” explains Very Well Health. Controlling odor extremely well, the Secret Clinical Strength deodorant “doesn’t transfer onto clothes” and keeps you smelling fresh when it counts most. Also, “ this antiperspirant wasn’t irritating to the skin” which is likely due to its skin-smoothing vitamin B5.

“This is officially my all-time favorite deodorant — it has, by far, exceeded my expectations,” says InStyle. With a “lasting power of up to 48 hours,” this deodorant provides unmatched protection and care with scents that are floral, sporty and invigorating. For all-day protection and nights that you need to be your best, Secret Clinical Strength always delivers.

2. SweatBlock Antiperspirant and Wipes

“One wipe can stop sweat for up to seven days,” relays People.com. With some “serious sweat-stopping power” the SweatBlock Antiperspirant is fragrance-free and not your typical deodorant as it doesn’t come in gel or stick form but rather as wipes. “And even though the wipes felt wet going on, the dry-down was quick and they left behind no marks on clothing or skin.”

SweatBlock Antiperspirant and Wipes
SweatBlock Antiperspirant and Wipes

Very Well Health explains, “SweatBlock Wipes were formulated by doctors to be strong enough to help hyperhidrosis, nervous sweating, hormonal sweating, or excessive perspiration from prescription drugs.” Even after working out, armpits still feel “completely dry while this wipe-style antiperspirant is ideal for being on-the-go or sprucing up real quick before a night out.”

“Containing aluminum chloride, this clinical-strength formula can reduce sweating for up to seven days,” writes Health. According to Dr. Saedi, the best way “to get the most out of these wipes is by applying them on dry skin at night and using stick deodorant during the day for odor protection.” Overall, SweatBlock Wipes are “a great over-the-counter option for people who have hyperhidrosis or excessive sweating.” 

3. Uriage Clinical Strength Deodorant

“Designed to last for 24 hours, Uriage Clinical Strength Deodorant has made waves for its fresh, long-lasting appeal,” claims InStyle. Doubling as an antiperspirant, this deodorant “goes on smoothly, is instantly absorbed, and doesn’t leave you feeling greasy.” Additional highlights include how its “hypoallergenic, has a fresh unisex scent, and how it’s infused with Uriage Thermal Water to nourish under-arm skin.”

Uriage Clinical Strength Deodorant
Uriage Clinical Strength Deodorant

“Even after a sweaty workout, the Uriage roll-on deodorant and antiperspirant kept our armpits smelling and feeling fresh for 24 hours,” writes Very Well Health. Formulated to tackle hyperhidrosis, this deodorant “controls sweating without blocking natural bodily processes while helping to heal irritated skin due to its trace minerals.” 

Health describes “Uriage Clinical Strength Deodorant as a roll-on antiperspirant that gives your pits the protection they need with just a few swipes.” Passing the sniff test, the “aluminum-based formula reduces underarm wetness while keeping odors at bay.” Offering a smooth application, the Uriage deodorant “doesn’t leave white marks on clothing” and helps keep you smelling fresh even after 24 hours. 

4. Vanicream Antiperspirant Deodorant

“If you are looking for a dermatologically-based solution for sensitive skin but are really after a combination formula, then this may be a great choice for you,” states Outlook India. As a classic twist-pop applicator, this clinical-strength deodorant “allows for gentle sweat-blocking action that is well tolerated by a wider range of skin types.” Additionally, this formula is “free from parabens, fragrances, and other irritants that are found in most deodorants.”

Vanicream Antiperspirant Deodorant
Vanicream Antiperspirant Deodorant

EJIS Inc says, “With Vanicream Antiperspirant Deodorant you can go about your day without worrying about sweat, odor, or irritated skin.” Offering effective 24-hour protection against sweat and odors, “this solid antiperspirant goes on smooth and leaves skin feeling soft without the use of chemicals like ethanol, talc, gluten, dyes, fragrance, lanolin, or parabens.”

“Albeit a gentle one, this extremely effective deodorant is designed for people with very sensitive or easily irritated skin,” explains Bustle. Containing “20 percent aluminum zirconium trichlorohydrex gly, this deodorant has the highest possible aluminum salt percentage of any over-the-counter product” and is a perfect option for those who find “most underarm products to be too harsh.” 

5. Certain Dri Clinical Prescription Strength Antiperspirant

“Certain Dri’s Prescription Strength Clinical Antiperspirant works wonders for minimizing sweat and odor-causing bacteria but can be irritating for sensitive skin types,” mentions Allure. With an aluminum chloride-based formula, this antiperspirant actively minimizes sweat production and is designed for those who struggle with excessive sweating.

Certain Dri Clinical Prescription Strength Antiperspirant
Certain Dri Clinical Prescription Strength Antiperspirant

Men’s Journal describes “Certain Dri as one of the toughest deodorants on the market.” As a roll-on antiperspirant, Certain Dri can “stop excessive sweating for up to three days with only a couple of strokes.” Considered the most effective antiperspirant one can buy without a prescription, Certain Dri is like having a personal bodyguard that keeps unpleasant wetness and odors at bay from morning to night.

“With 12 percent aluminum chloride, this roll-on antiperspirant from Certain Dri is one of the most powerful antiperspirants you can buy over the counter,” writes Bustle.com. Offering up to 72 hours of protection, this antiperspirant “should be applied on dry skin at bedtime or no later than 30 minutes after showering.” Additionally, Certain Dri recommends people to “avoid applying this antiperspirant after shaving as it can cause skin-irritation.”

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Note: This article was not paid for nor sponsored. StudyFinds is not connected to nor partnered with any of the brands mentioned and receives no compensation for its recommendations.

About Tim Lanoue

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